STAP1 and familial hyperaldosteronism: Recently, next-generation sequencing has demonstrated the FH phenotype due to occasional dominant mutations in apolipoprotein E (APOE) or signal-transducing adaptor family member 1 (STAP1), as well (Nordestgaard et al., 2013; Cuchel et al., 2014b; Fouchier et al., 2014; Berberich and Hegele, 2019).