The lncRNA FBXL19-AS1 is overexpressed in the cytoplasm of glioma microvessels and glioma endothelial cells (GECs) (Liu et al., 2020), and knockdown of FBXL19-AS1 increases the permeability of the BTB (Liu et al., 2020). Here, FBXL19 is linked to central nervous system cancer.