EGFR and cancer: Further,we explored the expression of the ERBBs in other cancers models by ONCOMINE database (Figure 1A) showed that ERBB1 mRNA level was significantly higher in the bladder, brain and CNS, head and neck, kidney, lung, lymphoma cancer tissues, and markedly lower in the breast, colorectal, gastric, myeloma, ovarian, and sarcoma cancers compared with the corresponding normal tissues.