HTRA1 and bladder transitional cell carcinoma: Based on cox regression model, 16 differentially expressed miRNAs and 287 differentially expressed mRNAs were identified to have statistically significant impact on the prognosis of BLCA, among which the top four miRNAs were hsa-let-7c, hsa-mir-99a, hsa-mir-125b-2, and hsa-mir-200c (Figures 3A–D), and the top four genes were HTRA1, ANXA1, EMP1, and FLNC (Figures 3E–H).