Mabuka and colleagues showed that plasma levels of B- cell activation factor (BAFF) increased after 7 days from the onset of HIV-1 viremia and declined at 14 days, whereas, plasma levels of CXCL13 were elevated at day 7 from the onset of HIV-1 viremia and increased throughout the infection period (38). The gene discussed is CXCL13; the disease is infection.