In yellow catfish, il-1r1 and tnfr1 mRNAs were significantly up-regulated at 6–120 h post-infection, and ifnγr1 mRNA was notably induced at 48 h, 72 h, and 120 h, whereas il-1r2 mRNA was distinctly induced only at 3 h. The gene discussed is IFNGR1; the disease is infection.