TNF and tuberculosis: Amongst markers with a significant decrease during treatment were acute phase proteins (CRP, SAA, pentraxin3, procalcitonin and ferritin) as well as the pro-inflammatory markers IP-10, IFN-γ, TNF-α, and MMP-1 which are in accordance with several other works reporting their potential in evaluating TB treatment and as markers of disease severity and bacterial burden (10, 36, 38–42).