Amongst markers with a significant decrease during treatment were acute phase proteins (CRP, SAA, pentraxin3, procalcitonin and ferritin) as well as the pro-inflammatory markers IP-10, IFN-γ, TNF-α, and MMP-1 which are in accordance with several other works reporting their potential in evaluating TB treatment and as markers of disease severity and bacterial burden (10, 36, 38–42). This evidence concerns the gene MMP1 and tuberculosis.