The relative mRNA expressions of Caspase-1 of HF zebrafish in SYDC-H treatment group and digoxin treatment group were significantly decreased compared with those of HF zebrafish in the model control group (0.85 ± 0.06 versus 105.95 ± 2.93; 0.56 ± 0.07 versus 105.95 ± 2.93, p < 0.001). This evidence concerns the gene CASP1 and hydrops fetalis.