The mRNA relative expressions of NF-κB of HF zebrafish in the SYDC-H treatment group and digoxin treatment group were significantly decreased compared with those of HF zebrafish in the model control group (1.39 ± 0.03 versus 16.65 ± 0.95, p < 0.001; 1.10 ± 0.05 versus 16.65 ± 0.95, p < 0.001). Here, NFKB1 is linked to hydrops fetalis.