TLR4 and epilepsy: There is an activation of the TLR4/NF-κB signaling axis in epilepsy as evident by an upregulated expression of TLR4 and NF-κB in epileptic animals and inhibiting the TLR4 and NF-κB represent a promising strategy against epileptic seizure (Liu et al., 2017; Shi et al., 2018; Qu et al., 2019).