Using the χ2 test, the significant associations of AD status were found with APOE genotype and MS4A4E (rs670139), but not with PICALM (rs3851179), EPHA1 (rs11771145), CR1 (rs3818361), CR1 (rs6656401), CD33 (rs3865444), ABCA7 (rs3764650), CLU (rs9331888), BIN1 (rs744373), or CD2AP (rs9349407) (Table 2). Here, BIN1 is linked to Alzheimer disease.