Using the χ2 test, the significant associations of AD status were found with APOE genotype and MS4A4E (rs670139), but not with PICALM (rs3851179), EPHA1 (rs11771145), CR1 (rs3818361), CR1 (rs6656401), CD33 (rs3865444), ABCA7 (rs3764650), CLU (rs9331888), BIN1 (rs744373), or CD2AP (rs9349407) (Table 2). The gene discussed is EPHA1; the disease is Alzheimer disease.