REST and neuropathy: Importantly, overexpression of REST/NRSF or dysregulation of its cellular expression pattern is related to many neuropathies: Medulloblastoma5,6, malignant pediatric brain tumor7, glioblastoma8,9, Huntington’s disease10–13, neuropathic pain14,15, Parkinson’s disease16, autism17, and fibromyalgia18.