The suppression or overexpression of ELOVL1 altered the levels of all analyzed esterified VLCFA species including TAG, CE, PL, SM and acyl-CoA in cultured cells (Fig. 5 and Supplementary Fig. S4 online), whereas VLCFA were accumulated only in TAG as esterified forms in CRC tissues (Fig. 3). This evidence concerns the gene ELOVL1 and colorectal carcinoma.