To fill this gap in the knowledge, we conducted this study with the following goals: (i) to quantify the FcgammaBP concentration in amniotic fluid samples from pregnant women with PPROM and PTL based on the phenotype of intra-amniotic inflammation; (ii) to quantify the FcgammaBP concentration in cervical fluid samples from pregnant women with PPROM and PTL based on the phenotype of intra-amniotic inflammation; and (iii) to assess the predictive value of FcgammaBP concentrations in amniotic and cervical fluids for intra-amniotic infection in pregnant women with PPROM and PTL. Here, FCGBP is linked to preterm premature rupture of the membranes.