EGF and neoplasm: Except for VEGF-C/D, many factors were reported to promote tumor lymphangiogenesis, such as VEGF-A14,15, hepatocyte growth factor (HGF)16, fibroblast growth factor(FGF)17, epidermal growth factor(EGF)18, platelet-derived growth factor-A(PDGF-A)19, and insulin-like growth factor(IGF)20.