To find the relationship between PEDF and LVD in NPC, we detected the PEDF expression and LVD by immunohistochemistry (IHC) in a NPC tissue microarray, which contains human nasopharyngeal cancer (22 cases), papilloma (15 cases), polyp (6 cases), hyperplasia, and inflammation (6 cases). The gene discussed is SERPINF1; the disease is polyp.