The highest risk rate of BS patients with intestinal involvement was IL-6 (> 7 pg/ml), then followed by the HGB (< 130 g/L), ESR (≥ 15 mm/H), gender (male), CRP (> 10 mg/L) and BDCAF (≥ 2) (shown in Table 6). This evidence concerns the gene IL6 and Bloom syndrome.