PRDM1 and neoplasm: Results revealed that tumor volume (Fig. 6a) and weight (Fig. 6b) were significantly enhanced in the presence of oe-KPNA2, whereas KPNA2 and c-FOS expression was upregulated and PRDM1 expression was downregulated (Fig. 6c, d) accompanied by accelerated cell proliferation (Fig. 6e) and suppressed cell apoptosis (Fig. 6f).