MYC and cancer: Therefore, Daniela et al. hypothesized that stabilization of lncRNAs CCAT1/2 by m6A modification amplified the effect of MYC expression levels in cancer cells by 2 separate mechanisms: (i) directly, both lncRNAs acted as super-enhancers for positive regulation of MYC mRNA [60]; (ii) indirectly, CCAT1/2 actedas microRNA sponges for MYC-targeting microRNAs let-7A and miR-145, respectively [61–64].