Furthermore, the PdgfrβCre + ;FAKY861F/Y861F but not PdgfrβCre + ;FAKY397F/Y397F mice had significantly reduced blood vessel density (as determined by the number of endomucin‐positive vessels per mm2 of age‐matched, size‐matched tumours) compared with PdgfrβCre + ;FAKWT/WT control mice (Fig. 1g, h). This evidence concerns the gene EMCN and neoplasm.