We focused on the role of MCP-1 in the apoptotic phenotype in tumours from PdgfrβCre + ;FAKY861F/Y861F mice since, in vitro, MCP-1 promotes mural cell recruitment [29] and in vivo pharmacological inhibition of MCP-1 reduces tumour growth and macrophage recruitment resulting in increased tumour necrosis [30], whilst loss of MCP-1 delays mammary tumourigenesis [31]. The gene discussed is CCL2; the disease is neoplasm.