MASP1 and leprosy: On the other hand, MASP1 haplotypes associated with lower MASP-1 and higher MASP-3 levels at baseline were associated with leprosy resistance, probably by decreasing mycobacteria infection, which relies on successful complement-driven opsonization and phagocytosis (Boldt et al., 2013; Weinschutz Mendes et al., 2020).