ACE and coronary artery disorder: Among the chronic non-communicable diseases, cardiovascular diseases, such as coronary artery disease (CAD), are important causes of morbidity and mortality, and account for 31% of causes of death in Brazil, being the leading cause of death in the world.(1,2) The pharmacological treatment of CAD involves the use of several drugs, such as antiplatelet agents, statins, beta-blockers, and angiotensin-converting enzyme inhibitors (ACEi).(3) The use of multiple drugs may cause inadequate administration and a higher incidence of adverse events.(4,5)