Besides ASCL1 and NEUROD1, YAP1 and POU2F3 have been reported as important regulators of SCLC, particularly for the non-NE phenotype (Baine et al., 2020; Huang et al., 2018; Ito et al., 2016; McColl et al., 2017; Song et al., 2020). Here, ASCL1 is linked to small cell lung carcinoma.