Tubular MCP-1/CCL2 expression is increased both in experimental and human DKD (Chow et al. 2006; Mezzano et al. 2003) and elevated urinary concentrations are independently associated with higher eGFR decline in diabetic CKD patients (Tam et al. 2009; Satirapoj et al. 2018). The gene discussed is CCL2; the disease is chronic kidney disease.