Deficiency of other sulfatases can result into dysmorphism, organomegaly, or dysostosis multiplex, resembling different mucopolysaccharidoses, like mucopolysaccharidosis II (M. Hunter; OMIM #309900), IIID (M. Sanfilippo‐D; OMIM #252940), or VI (Maroteaux‐Lamy‐Syndrom; OMIM #253200) for example due to deficiency of iduronate‐2‐sulfatase (EC 3.1.6.13), N‐acetylglucosamine‐6‐sulfatase (EC 3.1.6.14), or arylsulfatase B (ARSB) (EC 3.1.6.12), respectively.8 Here, ARSB is linked to mucopolysaccharidosis type 2.