The aqueous extract of green tea alleviated NAFLD in C57BL/6 mice by modulating the expression of miR-34a and miR-194, resulting in increasing the expression of SIRT1, PPAR-α, and insulin-induced gene 2 (Insig2), as well as decreasing the expression of apolipoprotein a5, 3-hydroxy-3-methyl glutaryl coenzyme A synthase (HMG-CoA synthase), and HMG-CoA reductase [110]. The gene discussed is INSIG2; the disease is metabolic dysfunction-associated steatotic liver disease.