MRC1 and spinal cord injury: For instance, it has been found that electroacupuncture reduced the proportion of M1 macrophages and the levels of TNF-α, IL-1 β, and IL-6 in rats with spinal cord injury and also increased the amount of IL-10 and M2 macrophages and upregulated the expression of the M2 markers CD206 and NT-3 [26, 27].