TNF and Alzheimer disease: The ELISA results showed that the protein expression of IL-1β and TNF-α in the brain was significantly decreased in the AD + BM25-H (IL-1β: 192.64 ± 22.49; TNF-α: 445.58 ± 33.73) and AD + BM25-M (IL-1β: 274.22 ± 56.87; TNF-α: 461.18 ± 100.14) groups compared with the AD + NS group (IL-1β: 505.69 ± 43.33; TNF-α: 714.65 ± 23.00) (p < 0.05) (Figure 8).