PGF and preeclampsia: Key measures of the predictive performance of the sFlt-1/PlGF ratio were also consistent in the Japanese and overall study cohorts, including the NPV for ruling out preeclampsia within 1 week (100% versus 98.6%, respectively), PPV for ruling in preeclampsia within 4 weeks (32.4% versus 30.3%), area under the ROC curve for any FAO within 4 weeks (82.6% versus 83.1%) and risk of imminent delivery in women with sFlt-1/PlGF ratio >38 versus ≤38 (2.8-fold higher versus 3.5-fold higher); for each of these measures, the 95% confidence intervals overlapped between cohorts [20].