Compared to those of the vehicle group, the mRNA expression levels of transforming growth factor beta (TGFB1), CCL2, interleukin-6 (IL6) and vascular endothelial growth factor alpha (VEGFA) were significantly downregulated in tumor samples of MMTV-PyVT mice treated with adiponectin-expressing EGFP+ cells (Fig. 7d). This evidence concerns the gene IL6 and neoplasm.