In functional aspects, mitochondrial oxidative stress in adipocytes is known to cause insulin resistance, and 6 mitochondrial proteins, electron transfer flavoprotein subunit alpha (ETFA), ferredoxin-2, 3-ketoacyl-CoA thiolase (ACAA2), long-chain specific acyl-CoA dehydrogenase (ACADVL), acyl-CoA dehydrogenase family member 9 (ACAD9), and carnitine O-palmitoyltransferase 2 (CTP2), were also listed in the proteins found only in anti-Gal-9 antibody-precipitated sample (Supplementary Table 1d and 2). This evidence concerns the gene ETFA and Insulin resistance.