Our results indicate that susceptibility to NODAT might be monitored by genotyping KTRs who developed diabetes compared with KTRs who did not develop diabetes for selected major Th 1(IFNG)/ Th-2 (IL-4)/TGFB, T-reg in addition to IL-6, macrophage derived cytokines. This evidence concerns the gene TGFB1 and diabetes mellitus.