PHACTR1 and brain ischemia: Particularly, we focused on a potential Phactr1 variant enrichment as determinant for different vascular traits such as (1) embryonic vasculogenesis and vessel density indirectly measured through CBF in naive mice pre-surgery 41 (Fig. 5A,B, Table S1); (2) PcomA size during brain ischemia (Fig. 5C, Table 4) and (3) leptomeningeal microcollateral length and junction density during subacute hypoperfusion (7d) (Fig. 5D–F, Tables S2 and S3).