SORL1 and Alzheimer disease: However, in cerebella from AD patients, 93.0% of all PCs showed a lack of SORL1-38b expression (p < 0.001 compared to non-AD distribution in group 0), accompanied by a significant reduction in the number of PCs corresponding to groups I (5.5%; p = 0.0177) and II (1.5%; p = 0.0002) with no cells assigned to group III (Fig. 4b).