Bioinformatics analysis of the adhesion molecules in MM patients using OncomineTM database revealed that ITGA4 and ITGB7 were significantly upregulated in MM tissues as compared to NPCs, while ITGB3 and CDH1 expression was not different (Fig. 5C; see also Additional file 2: Fig. S19B), suggesting the role of ITGA4 and ITGB7 in MM cell adhesion. This evidence concerns the gene ITGB7 and Miyoshi myopathy.