KDR and neoplasm: Inactivation of VEGFR2 Y949 phosphorylation in TAg-VEGFR2Y949F/Y949F mice abolishes all effects of siANGPTL4 on the inhibition of tumor proliferation and metastasis and the suppression of vascular angiogenesis, suggesting that VEGFR2 pY949 is responsible for the tumor-suppressive effects of siANGPTL4 in ovarian cancer.