As the most common type of CMT, CMT1 is linked with PMP22,[9]MPZ,[10]EGR2,[11] lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF),[12] and neurofilament light chain polypeptide genes (NEFL),[13] while CMT1A is mainly caused by a 1.5 Mb duplication on chromosome 17p11.2 that includes the PMP22 gene.[14] However, some patients with mutations of PMP2, MPZ, periaxin gene (PRX), or EGR2 may show more severe CMT subtype, that is, CMT3.[10,15–17]. Here, LITAF is linked to Charcot-Marie-Tooth disease.