On the 8th day of hospitalization, methylprednisolone pulse therapy (500 mg/day for 3 days, followed by 240 mg/day for 3 days) and gamma globulin (25 g/day for 5 days) were infused intravenously to treat severe SLE and anti-NXP2-positive myositis. The gene discussed is MORC3; the disease is myositis disease.