In ACC relative to normal tissue, RBM15, ZC3H3, YTDHF1, YTDHF2, and ALBH5 were overexpressed, and the expression levels of KIAA1429, YTHDC1, HNRNPC, WTAP, METTL3, and FTO in ACC were low. Here, METTL3 is linked to adrenal cortex carcinoma.