In addition, increased WHtR was reported to significantly correlate with increased cardiometabolic risk factors,[19] hypertension,[20] and mortality.[21] One recent study found that individuals with NAFLD showed greater improvements in liver function and insulin sensitivity after moderate, diet-induced weight loss than individuals without NAFLD.[22] Above all, this study highlights the importance of including weight management in treatment plans for T2DM patients with NAFLD. Here, INS is linked to type 2 diabetes mellitus.