According to this study, CD4 count was identified as a determinant factor for TB in which patients with a CD4 count of 201–349 cells/mm3 were more likely to develop TB after ART initiation as compared with those with a CD4 count of ≥350 cells/mm3 (AOR: 3.383 95% CI: 1.520, 7.528). This evidence concerns the gene CD4 and tuberculosis.