LvCaP-1 expressed NKX3-1, HOXB13 (mutated G84E), FOLH1, KLK2, and KLK3 (Figure 3, A and E, and Figure 8C), but with only a low level of PSA secretion (i.e., serum PSA of 1.4 ± 0.4 ng/mL/g tumor; Supplemental Figure 1A). This evidence concerns the gene KLK3 and neoplasm.