WDR81 and congenital hydrocephalus: In conclusion, based on the clinical presentations and genetic findings, we proposed that our patient's phenotype is consistent with autosomal recessive HYC3, and the condition was due to the compound heterozygous frameshift variants in WDR81, c.146_147insG and c.673delC in exon 1 affected N‐domain of WDR81 protein.