TYR and melanoma: To better evaluate the validity of our candidate genes identified using this workflow, we added well‐established and validated BRAFi‐resistant genes (NRP1, AXL, ZEB1, and LPAR1) (Müller et al,2014; Konermann et al,2015; Rizzolio et al,2018) and five genes associated with melanoma cell differentiation (MITF, OCA2, MLANA, TYR, and TYRP1) (Levy et al,2006).