The fact that underlying cardiovascular, pulmonary, and renal disease have been associated with significantly increased mortality in COVID-19 patients and that abnormalities of various plasma inflammatory biomarkers (eg, lymphocyte count, C-reactive protein (CRP), procalcitonin, D-dimer, and aspartate aminotransferase) appear to be widespread [3,4,6,7] highlights the multisystem nature of the disease and suggests that immune-mediated cytokine signaling and development of cytokine storm play a key role in driving disease progression [7]. This evidence concerns the gene CRP and COVID-19.