We also detected the highest numbers of CD3+ and CD8+ TILs, of which up to 40% was associated with a cytolytic functional profile, in Group C. Coupled with a low number of tumor-infiltrating Treg cells, Group C displayed a more favorable OC TME for tumor control than other groups as demonstrated by a significantly higher ratio of CD8+ TILs to tumor-infiltrating Treg cells. This evidence concerns the gene CD8A and neoplasm.