SH2D1B and bipolar disorder: However, among these genes altered in COVID-19, two similarly affected genes (VCAN, RHOBTB3) were also observed in bipolar disorder and PTSD, five genes (PTGDR, SH2D1B, AKR1C3, YES1 and RHOBTB3) were shared between bipolar disorder and schizophrenia and one gene (RHOBTB3) is commonly dysregulated among all of three psychiatric conditions and COVID-19.