AQP4 and neoplasm: In addition, its expression was higher in patients in the first stage andminor tumor size, suggesting its relation with a better prognosis.AQP4-AS1 expression was not previously analyzed in breastcancer, but the gene AQP4 expression has the same profile of theAQP4-AS1, with low expression in tumor and the expressionassociated with better prognosis (Shi etal., 2011; Zhu etal., 2019).