Given this context, different variables have been identified to predict whether a person with psoriasis may develop PsA, including clinical characteristics of psoriasis such as the severity of psoriasis or the presence of certain features of psoriasis (e. g., scalp lesions, nail disease, and intergluteal/perianal psoriasis), the presence of soluble biomarkers, like highly sensitive C-reactive protein or certain susceptibility genes [9–11]. This evidence concerns the gene CRP and psoriasis.