HOTTIP and central nervous system cancer: Moreover, several of them (e.g., HOXA1, A5, A6, A7, A10, D9, and D10) were expressed in most IDHwt glioma samples, constituting thus the core HOX signature in IDHwt samples, whereas HOXB1, HOXC12, HOTTIP, and HOXB‐AS4 were not reactivated, as shown before (Fig. 1C, Tables S3 and S4).