MYCN and neuroblastoma: This was correlated with Histone H3 acetyl‐Lysine 27 (H3K27ac) and monomethylated H3K4 (H3K4me1), histone modifications that are associated with active enhancer regions (Rada‐Iglesias et al, 2011), indicating that MYCN directly contributes to increasing the expression of netrin‐3 in NB (Figs 3D and EV2F).