Furthermore, the other three hub genes, IL2RB, XCR1 and CXCR6, have been reported to be related with the prognosis of other cancers, such as early breast cancer,39 salivary adenoid cystic carcinoma,40 bladder and hepatocellular cancers.41, 42. Here, CXCR6 is linked to hepatocellular carcinoma.